Baikal skullcap root extract powder standardized to 30–85% baicalin

Baikal Skullcap Extract 30–85% Baicalin

Baikal Skullcap Extract is a standardized botanical ingredient produced from the root of Scutellaria baicalensis Georgi, a member of the Lamiaceae family. Also known as Chinese skullcap or Huang Qin extract, it is supplied as a concentrated powder standardized against baicalin, one of the characteristic flavone glucuronides naturally present in the root.

Essencefield supplies standardized grades across the 30–85% range, with 85% representing the primary high-assay commercial specification. The high-assay grade is quantified by HPLC and is suited to concentrated formulations where a defined marker input and lower total botanical inclusion are important.

SKU: BOT-STX-0103 Categories: Standardized Extracts, Polyphenol & Flavonoid Extracts Tags: Antioxidant Support, Baicalin, Baikal Skullcap, Dietary Supplements, Flavonoids

Ingredient Profile & Common Uses

Scutellaria baicalensis root contains a characteristic flavonoid profile including baicalin, baicalein, wogonin, wogonoside, and related flavones. A standardized extract differs commercially from ordinary skullcap root powder because extraction and concentration produce a controlled marker level rather than simply supplying milled botanical material. Its commercial identity is therefore defined by the root source, standardized-extract format, and compound-specific assay.

The 30–85% specification range provides different concentration levels within the same botanical-extract category. Lower-assay material retains a larger proportion of accompanying extract solids, while concentrated grades provide more marker compound per unit weight. This allows formulators to select an appropriate grade according to target inclusion level, available formulation space, and the required standardized botanical input.

Baikal skullcap extract is used in dietary supplements, botanical premixes, powdered formulations, and selected cosmetic systems. Concentrated material has a naturally yellow to yellow-brown appearance and a distinctly bitter botanical taste. It should be treated as a dispersible ingredient rather than assumed to produce a transparent aqueous solution, making wetting, sedimentation, color, and flavor relevant during product development.

Application Areas

Capsules & Tablets

Standardized extract is suitable for capsule and tablet systems requiring a controlled marker input. Concentrated grades can reduce the total botanical mass needed to reach the intended formulation target.

Botanical Premixes

The extract can be incorporated into multi-ingredient botanical blends and dry premixes. Staged or geometric blending is useful when a concentrated grade represents only a small proportion of the final batch.

Powdered & Reconstituted Formulations

Baikal skullcap extract can be used in sachets, drink powders, and other dry systems intended for reconstitution. Bitterness, yellow coloration, dispersibility, and potential sedimentation should be evaluated during development.

Selected Cosmetic Formulations

Standardized root extract may also be evaluated in topical systems. Dispersion method, formulation pH, natural color contribution, and compatibility with other ingredients are relevant during prototype and stability work.

Typical Specifications

Item	Specification
Product Name	Baikal Skullcap Extract
Botanical Name	Scutellaria baicalensis Georgi
Botanical Family	Lamiaceae
Common Names	Baikal Skullcap · Chinese Skullcap · Huang Qin
Plant Part	Root
Ingredient Type	Standardized Botanical Extract
Product Form	Powder
Baicalin Specification	30–85%
Lower Standardized Grade	30%
Primary High-Assay Grade	85%
Marker Compound	Baicalin
Assay Method — 85% Grade	HPLC
85% Grade Appearance	Fine yellow to yellow-brown powder
85% Grade Sensory Profile	Characteristic botanical odor with bitter taste
85% Grade Water Behavior	Partially soluble / dispersible; not intended as a clear aqueous solution
Botanical Extract Reference CAS	94279-99-9
Baicalin Reference CAS	21967-41-9
Baicalin Molecular Formula	C21H18O11
Baicalin Molecular Weight	446.4 g/mol

Marker Compounds & Standardization

Baicalin is a characteristic flavone glucuronide of Scutellaria baicalensis root and is chemically the 7-O-glucuronide of baicalein. The root also contains related flavones and glucuronides including baicalein, wogonin, wogonoside, and oroxylin-related compounds, producing a chromatographic profile that is distinct from nonspecific total-flavonoid extracts.

Commercial standardization refers to the measured concentration of a defined compound rather than total flavonoids. For the high-assay grade, HPLC provides selective quantification against structurally related constituents and gives buyers a more specific analytical definition of the ingredient.

The standardized range therefore represents different concentrations of one marker within a multi-component botanical extract. Even highly concentrated material remains a botanical mixture rather than pure baicalin. CAS 21967-41-9, molecular formula C21H18O11, and molecular weight 446.4 g/mol describe the reference compound rather than the complete extract.

Technical & Quality Considerations

Quality evaluation should establish botanical identity, the declared marker concentration, and the corresponding analytical method. Species verification is particularly relevant because the commercial term “skullcap” may refer to different Scutellaria species. Procurement and QA teams should therefore distinguish S. baicalensis root extract from other skullcap materials before comparing assay values or formulation performance.

The concentrated powder has a yellow to yellow-brown appearance and a bitter sensory profile. Its aqueous behavior is influenced by the physicochemical properties of the marker and the surrounding extract matrix, so wetting, turbidity, sedimentation, and pH should be evaluated in beverage or reconstituted systems rather than assuming direct dissolution.

For dry formulations, low inclusion levels can make blend uniformity a practical scale-up consideration. Geometric dilution or premixing with a compatible formulation ingredient can improve distribution before final blending, capsule filling, or tableting. In liquid systems, development should focus on dispersion method, pH, physical stability, color, and flavor masking.

Packaging & Commercial Supply

Essencefield supports product evaluation, formulation trials, commercial orders, and ongoing ingredient supply. Packaging, storage, and shipping arrangements are determined by product characteristics, order quantity, stability requirements, and destination-market needs.

Supply Item	General Information
Sample	Available upon request for formulation, testing, and supplier evaluation
Order Quantities	100 g · 1 kg · 5 kg · 25 kg · 100 kg · 500 kg · Bulk
Sample Lead Time	Typically 5–7 days after sample confirmation
Production Lead Time	Typically 15–30 days after order and specification confirmation
Packaging	Suitable protective inner packaging with bags, cartons, drums, or other appropriate outer packaging
Storage	Store in tightly sealed, suitable protective packaging in a cool, dry environment. Protect from moisture, heat, and direct sunlight. Specific storage conditions follow the approved product specification.
Documentation	COA · Product Specification · TDS · SDS · Applicable declarations (as applicable)

Final order quantities, lead times, packaging, documentation, and shipping arrangements are confirmed according to the selected product and commercial requirements.