White Willow Bark Extract 15–50% Salicin

White Willow Bark Extract is a standardized botanical ingredient produced from the bark of Salix alba L., a species of the Salicaceae family. Supplied as an extract powder, it differs from untreated willow bark by providing a controlled concentration of salicin, the principal marker used to define commercial standardized grades.

Essencefield supplies 15%, 25%, and 50% standardized grades quantified by HPLC. The 15% specification serves as the primary commercial grade, while higher concentrations provide greater marker density for formulations where lower botanical inclusion weight or additional formulation space is important.

Ingredient Profile & Common Uses

White willow bark provides the raw botanical material for this standardized extract. Processing concentrates characteristic bark constituents into a powdered ingredient with a defined analytical marker, distinguishing it from simple milled bark. It also remains chemically and commercially different from isolated high-purity salicin because the extract retains a broader botanical matrix.

Different assay levels allow formulators to control how much extract is needed to deliver a defined marker input. Higher-assay material reduces botanical inclusion weight, while lower-assay material contributes a greater proportion of accompanying bark-extract solids. Grade selection can therefore influence formulation density, ingredient cost per target marker level, available capsule or tablet space, and overall product positioning.

The standardized extract is primarily used in dietary supplements and multi-botanical formulations requiring measurable botanical-marker input. Its naturally bitter sensory profile is relevant in powders and other directly consumed formats, while particle characteristics and accompanying extract solids can affect blend uniformity, powder handling, and dispersion during product development.

Application Areas

Capsules

The extract is suitable for hard-capsule botanical supplements where a defined marker contribution is required. Higher-assay material can reduce the amount of extract needed per serving.

Tablets

Standardized grades can be incorporated into compressed products, with assay selection influencing marker density and the formulation space available for excipients and companion ingredients.

Multi-Botanical Formulas

The ingredient can be combined with other standardized plant extracts in formulas where developers require controlled botanical-marker inputs rather than relying on unstandardized botanical powders.

Powder & Sachet Formulations

Powdered supplement systems can incorporate the extract where a defined willow-bark marker profile is required. Bitterness, dispersion, and blend uniformity should be evaluated during formulation development.

Typical Specifications

Specification	Information
Product Name	White Willow Bark Extract
Botanical Name	Salix alba L.
Botanical Family	Salicaceae
Common Name	White Willow
Plant Part	Bark
Ingredient Type	Standardized Botanical Extract
Product Form	Powder
Standardized Marker	Salicin
Available Grades	15% · 25% · 50% Salicin
Primary Commercial Grade	15% Salicin
Assay Method	HPLC
White Willow Bark Extract CAS Reference	84082-82-6
EC Reference	282-029-0
Salicin CAS	138-52-3
Salicin Molecular Formula	C₁₃H₁₈O₇
Salicin Molecular Weight	286.28 g/mol
Salicin PubChem CID	439503

Salicin Standardization & Willow Bark Constituents

Salicin is a phenolic glycoside used as the principal quantitative marker for standardized willow bark extract. Its commercial value as a marker is analytical: it provides a measurable basis for comparing extract concentration without treating the entire botanical matrix as a single purified compound.

Standardization describes the measured proportion of this marker within the finished botanical material. Increasing assay strength therefore raises marker density per gram of extract while decreasing the quantity of material required to reach a defined formulation target.

Willow bark also contains other phenolic constituents, including salicin-related glycosides such as salicortin and tremulacin, together with flavonoids, catechins, and condensed tannin constituents. These compounds contribute to the broader chemical profile but are not interchangeable with the declared assay.

The 15–50% product range is therefore positioned as standardized botanical extract rather than isolated or near-pure salicin.

Technical & Quality Considerations

Analytical evaluation should verify agreement between botanical identity, bark source, declared assay grade, and chromatographic result. HPLC provides quantitative marker control by separating the target analyte from the surrounding botanical matrix, making it suitable for standardized-grade verification and incoming ingredient assessment.

Assay strength can also influence physical and formulation behavior. Higher-concentration material delivers more marker per gram, whereas lower-assay grades contribute more accompanying extract solids for the same target marker input. Differences in botanical solids can affect color, bitterness, dispersion, powder handling, and the overall sensory contribution of the ingredient.

During scale-up, R&D teams should evaluate blend uniformity at the intended inclusion rate, particularly when concentrated grades are used at relatively low levels. Capsule and tablet systems require attention to flow and dose uniformity, while directly consumed powders require additional assessment of bitterness, dispersion, and interaction with other botanical ingredients.

Packaging & Commercial Supply

Essencefield supports product evaluation, formulation trials, commercial orders, and ongoing ingredient supply. Packaging, storage, and shipping arrangements are determined by product characteristics, order quantity, stability requirements, and destination-market needs.

Supply Item	General Information
Sample	Available upon request for formulation, testing, and supplier evaluation
Order Quantities	100 g · 1 kg · 5 kg · 25 kg · 100 kg · 500 kg · Bulk
Sample Lead Time	Typically 5–7 days after sample confirmation
Production Lead Time	Typically 15–30 days after order and specification confirmation
Packaging	Suitable protective inner packaging with bags, cartons, drums, or other appropriate outer packaging
Storage	Store in tightly sealed, suitable protective packaging in a cool, dry environment. Protect from moisture, heat, and direct sunlight. Specific storage conditions follow the approved product specification.
Documentation	COA · Product Specification · TDS · SDS · Applicable declarations (as applicable)

Final order quantities, lead times, packaging, documentation, and shipping arrangements are confirmed according to the selected product and commercial requirements.