Andrographis Paniculata Extract Powder

Name: Andrographis Extract Powder | 10% & 50% Andrographolide
SKU: BOT-BEX-0165

Andrographis Paniculata Extract Powder is produced from the aerial parts of Andrographis paniculata (Burm.f.) Wall. ex Nees, an Acanthaceae botanical also known as andrographis or kalmegh. The extract is characterized by its diterpene lactone profile, with andrographolide serving as the principal quantitative marker used for commercial standardization.

Essencefield supplies 10% and 50% andrographolide grades measured by HPLC. The lower-assay grade is suited to conventional botanical formulations containing more of the original plant matrix, while the concentrated grade reduces ingredient input where formula space is limited. Botanical identity can be evaluated by TLC or chromatographic fingerprinting alongside quantitative assay.

SKU: BOT-BEX-0165 Categories: Botanical Extracts, Leaf & Herb Extracts Tags: Andrographis, Andrographis paniculata, Andrographolides, Diterpene Lactones, Diterpenoids, Immune Support

Ingredient Profile & Common Uses

The commercial extract is produced from aerial plant material, primarily leaf and stem, rather than being a simple milled herb powder. Its identity is defined by both the source botanical and a measured marker concentration. This distinction is important for procurement teams comparing standardized material with whole-herb powder or non-assay-controlled ratio extracts.

Grade selection depends mainly on the required marker contribution and available dosage-form space. A 10% material provides greater botanical solids and is practical in conventional herbal blends, while the 50% option delivers a more concentrated input for compact capsules, tablets, and dry premixes. The two grades therefore serve different formulation and cost-in-use requirements rather than representing interchangeable specifications.

Andrographis has a characteristically intense bitter taste. Encapsulated, coated, and dry-blend formats can help limit direct sensory exposure. In aqueous systems, incomplete dissolution, haze, or sediment may occur, so formulation work should evaluate wetting, dispersion, suspension stability, and flavor masking under actual use conditions.

Application Areas

Botanical Capsules

The 10% grade is suitable for capsule formulations where marker content must be balanced with total botanical load, capsule capacity, powder density, and filling performance.

Concentrated Tablets

The higher-assay grade reduces extract input where tablet size is constrained. Development should evaluate flow, compression behavior, blend uniformity, and coating requirements.

Multi-Ingredient Botanical Formulas

The extract can be combined with other standardized botanicals in dry formulations requiring a defined marker contribution and consistent ingredient identity.

Powder Premixes

Concentrated material can be incorporated into premixes where a relatively small ingredient input must be distributed evenly throughout a larger dry formulation.

Stick Packs and Dispersible Powders

Powder systems can incorporate andrographis where bitterness, wetting, haze, visible sediment, and suspension behavior are addressed through the finished formulation.

Typical Specifications

Parameter	Specification
Product Name	Andrographis Paniculata Extract Powder
Botanical Name	Andrographis paniculata (Burm.f.) Wall. ex Nees
Botanical Family	Acanthaceae
Common Names	Andrographis · Kalmegh · Green Chiretta
Plant Part	Aerial parts, primarily leaf and stem
Ingredient Type	Standardized botanical extract
Product Form	Powder
Available Grades	10% · 50% Andrographolide
Primary Market Grade	10% Andrographolide
Concentrated Grade	50% Andrographolide
Primary Marker	Andrographolide
Assay Method	HPLC
Botanical Identification	TLC and/or HPLC chromatographic fingerprint
Appearance — 10% Grade	Yellow-brown powder
Appearance — 50% Grade	Tan to brown powder
Sensory Profile	Characteristically bitter
Particle Size	Typically 80 mesh
Aqueous Behavior	Dispersible botanical powder; haze or sediment may occur

Marker Compounds & Standardization

Andrographolide belongs to the labdane diterpenoid lactone class and is the principal quantitative marker associated with commercial Andrographis paniculata extracts. The botanical also contains related diterpenes, including neoandrographolide and deoxyandrographolide derivatives. This constituent profile helps distinguish an assay-controlled extract from ordinary powdered aerial plant material.

A specification such as 10% andrographolide describes the measured concentration of a defined marker. It is not equivalent to an extraction ratio such as 10:1. Extract ratio describes the relationship between starting botanical material and resulting extract, whereas a percentage assay quantifies a constituent in the finished ingredient. These two specification systems should therefore not be compared as though they measure the same attribute.

Concentration also affects cost-in-use and formulation input. At the same theoretical marker target, a 50% material requires one-fifth of the ingredient weight of a 10% material. Lower input can free dosage-form space, but it places greater importance on blend uniformity when the concentrated ingredient represents only a small percentage of the finished batch.

Technical & Quality Considerations

Botanical authentication and quantitative assay are the main analytical controls for this ingredient. TLC can support identity testing, while HPLC fingerprinting provides broader chromatographic profile information. Quantitative HPLC is used to determine the marker concentration and differentiate the available assay grades.

Physical behavior should be evaluated alongside chemistry. Lower-assay material contributes more botanical matrix and powder mass at an equivalent marker target, which can influence color, bitterness, density, flow, and finished-product appearance. Particle distribution, wetting, dispersibility, and sedimentation are particularly relevant when the extract is used outside conventional capsules or tablets.

During commercial scale-up, ingredient input should be calculated from the actual assay and matched with an appropriate blending sequence. The concentrated grade may benefit from staged dilution before final blending when inclusion is low. Capsule and tablet projects should assess fill or compression performance, while aqueous powder systems should evaluate wetting, sedimentation, sensory masking, and marker recovery under real processing conditions.

Packaging & Commercial Supply

Essencefield supports samples, development quantities, commercial orders, and repeat ingredient supply for product evaluation, formulation, and ongoing sourcing. Packaging, storage, and shipping conditions are selected according to ingredient characteristics, order quantity, stability requirements, and destination-market needs.

Supply Item	General Information
Sample	Available for formulation, testing, and supplier evaluation
Order Quantities	Sample · 100 g · 1 kg · 5 kg · 25 kg · 100 kg · 500 kg · Bulk
Sample Lead Time	5–7 days
Production Lead Time	15–30 days
Packaging	Sealed food-grade or suitable protective inner packaging with drum, carton, bag, or other appropriate outer packaging
Storage	According to the approved product specification and ingredient stability requirements
Documentation	COA · Product Specification · TDS · SDS · Applicable declarations

Available quantities, packaging format, net weight, storage conditions, analytical requirements, documentation, and shipping arrangements are confirmed according to the selected ingredient and commercial order.