Flavonoid Standardization & Grades
Flavonoids are plant phenols built on a three-ring skeleton. In Passiflora incarnata the main members are C-glycosyl flavones, in which a sugar is joined to the flavone skeleton through a carbon bond that resists hydrolysis. The best known are vitexin, isovitexin, orientin and isoorientin. The grade expresses the total flavonoid response on vitexin as the reference, which fixes the basis of the percentage. The botanical entity is Passiflora incarnata L., a climbing vine of the Passifloraceae, and the part used is the aerial herb.
For passionflower, the grade is a single level at 4%, so there is no tier to choose between. The choice is between passionflower materials. The herb is also supplied as a 10:1 ratio extract, the Passionflower Extract Powder, which carries no marker figure, as a milled herb, the Passionflower Herb Powder, and as the purified flavone Isoorientin 98%. Passionflower extract at this level is a flavonoid concentrate of the herb, and passionflower extract is a simple name for several differently standardized products. Industry extracts of this plant are commonly standardized either to isovitexin by HPLC or to vitexin by UV, and a figure expressed on one basis is not comparable with one expressed on the other.












