Total Bioflavonoid Standardization & Grades
Bioflavonoids is the trade name for the flavonoid fraction of citrus fruit. In sweet orange peel it is dominated by hesperidin, a flavanone rutinoside, with narirutin as the second main component and smaller amounts of didymin and polymethoxylated flavones. A UV assay adds these into one number. The botanical entity is Citrus sinensis (Mill.) Pers., and the extract is standardized to the class because it is the defining phenolic fraction of the peel.
| Grade | Assay & Method | Where It Fits |
|---|---|---|
| 40% Total Bioflavonoids | UV | Blends and drink premixes |
| 90% Total Bioflavonoids | UV | Capsules and tablets, very small fill |
Grade choice for citrus bioflavonoids extract follows dose and fill weight. The 90% grade carries more than twice the bioflavonoid load of the 40% grade per gram, and a capsule reaches its target in a very small fill, while the 40% grade is bulkier, lighter in color and easier to disperse in a blend. Citrus is also supplied as 10:1 ratio extracts with no marker figure: the Citrus Bioflavonoid Extract Powder, the Orange Peel Extract Powder and the Bitter Orange Peel Extract Powder. The standardized extract is the row to use when a bioflavonoid figure has to appear in the specification.












