Eleuthero Extract 0.8–2% Eleutherosides

The root and rhizome of Eleutherococcus senticosus, the Siberian ginseng of northeastern Asia, are the only starting material in this extract, and the leaf, stem bark and fruit are excluded. Ethanol extraction takes up the glycosides and lignans of the root, and the concentrate is dried to a light brown powder.

Eleutherosides are measured by HPLC, with a primary grade of 2% and a lower grade of 0.8%. The powder is 80 mesh and slightly soluble in water. The 2% grade fits capsules and tablets that need a small fill, while the 0.8% grade fits drink powders and blends in which the root matrix is wanted.

SKU: BOT-STX-0144 Category: Standardized Extracts Tags: Bars & Bakery, Dry Blends & Premixes, Eleuthero, Ethanol Extracted, Root & Rhizome, Standardized Extracts

Eleutheroside Standardization & Grades

Eleutherosides are a group of chemically unrelated compounds that share a name and a source. Eleutheroside B, also called syringin, is a phenylpropanoid glycoside, eleutheroside E is the lignan syringaresinol diglucoside, and eleutheroside B1 is a coumarin glycoside related to isofraxidin. The botanical entity is Eleutherococcus senticosus (Rupr. & Maxim.) Maxim., and the eleuthero extract is standardized to the eleutherosides because they are the identity compounds of the pharmacopoeial root, and the assay sums eleutherosides B and E.

Grade	Assay & Method	Where It Fits
0.8% Eleutherosides	HPLC	Drink powders and blends, higher inclusion
2% Eleutherosides	HPLC	Capsules and tablets, small fill weight

Grade choice follows dose and fill weight. The 2% grade carries two and a half times the eleutheroside load of the 0.8% grade per gram, so a capsule reaches its target with less powder, while the 0.8% grade is bulkier and keeps more of the root’s sugars and phenolics. Eleuthero is also supplied as a 10:1 ratio extract with no marker figure, the Acanthopanax Senticosus Extract Powder, and as single compounds, Isofraxidin 98% and Syringaresinol Diglucoside 98%. The standardized extract is the row to use when an eleutheroside figure has to appear in the specification of the eleuthero extract.

Eleutheroside Analysis & Purity Risks

HPLC separates eleutheroside B and eleutheroside E on a reversed-phase column and quantifies the peaks against reference standards, with UV detection at a low wavelength where both chromophores absorb. The result is the sum of the named eleutherosides. A UV total would count other phenolics, and a gravimetric glycoside figure would count sugars, so neither can be converted into the HPLC sum.

For identity, the fingerprint of the root is read beside the sum. Syringin and syringaresinol diglucoside are the two characteristic peaks, and isofraxidin glycosides and chlorogenic acid appear as neighbors. The pattern separates the root from other Araliaceae roots, and the ratio of eleutheroside B to eleutheroside E is part of the identity statement.

Purity risks follow from the botanical group. Despite its trade name, Siberian ginseng is not a Panax species and does not contain ginsenosides. Acanthopanax gracilistylus and other related species are traded under similar names, and the root bark of the unrelated Periploca sepium, known as Chinese silk vine, has been reported as a substitute in the trade because it carries cardiac glycosides that the true root does not. The stated species, the stated root part and the eleutheroside fingerprint therefore protect identity better than one percentage does.

Sample preparation uses an aqueous alcohol extraction followed by filtration, and the samples are injected promptly. Eleutheroside E is a diglucoside and dissolves more easily than the aglycone, while syringin is stable in neutral solution.

Raw material handling also matters. Roots are harvested in autumn, washed and dried, and the eleutheroside content varies with the age of the plant and the site. Well-dried root is woody and light brown, and a damp lot shows mold and lower eleutheroside content.

Typical Specifications

Specification Item	Product Information
Latin Name	Eleutherococcus senticosus
Plant Part	Root & Rhizome
Processing	Ethanol Extraction
Compound Class	Lignans, Polyphenols
Common Name	Eleuthero, Siberian Ginseng
Ingredient Type	Standardized Extract
Marker Compound(s)	Eleutherosides (eleutheroside B and eleutheroside E)
Primary Grade	2% Eleutherosides (HPLC)
Available Grades	0.8% · 2% Eleutherosides (HPLC)
Appearance	Light Brown powder
Solubility / Dispersibility	Slightly Soluble in Water
Quality Parameters
Moisture (LOD)	≤5.0%
Total Ash	≤5.0%
Particle Size	80 mesh
Heavy Metals	Lead ≤2 ppm · Arsenic ≤1 ppm · Cadmium ≤1 ppm · Mercury ≤0.1 ppm
Microbiology	TPC ≤1,000 cfu/g · Yeast & Mold ≤100 cfu/g · E. coli Negative · Salmonella Negative/25 g
Shelf Life	24 months in unopened original packaging, cool and dry storage

Applications by Grade

2% Grade for Compact Capsules

The 2% grade of eleuthero extract reaches an eleutheroside target in a small fill, which suits compact capsules. The powder is slightly hygroscopic and woody, so fill in a dry room, use a flow agent and seal the capsules in a desiccated bottle.

0.8% Grade in Drink Powders

The 0.8% grade is bulky enough to carry in stick-pack drink powders at a practical gram weight. It gives a light brown, slightly hazy cup with a woody, mildly bitter taste that suits citrus, ginger or honey flavors.

2% Grade in Tablet Blends

Tablets of the 2% grade need a dry binder and a glidant, and a film coat covers the earthy taste of the root. Check hardness and disintegration after storage, because the sugar-bearing powder softens in humid air.

0.8% Grade in Tea-Style Instant Blends

Instant blends in stick format use the 0.8% grade with green tea, ginger or ginseng-free herb bases. The extract steeps quickly, and a short stir produces an even cup without clumping. Because the eleuthero extract is only slightly soluble, a fine grind avoids a sandy layer at the bottom of the cup.

0.8% Grade in Bar Blends

In cold-pressed bars the 0.8% grade is blended into the dry fraction before the syrup is added. The woody flavor sits under cocoa, nut and date notes, and the tan color is invisible in dark bases. Cold pressing protects the glycosides from the heat of baking.

2% Grade in Sachet Dilutions

Sachets of the 2% grade call for stepwise dilution with a bulking carrier so the filler can weigh an accurate dose. A foil laminate with low moisture transmission keeps the powder free-flowing through shelf life.

Technical & Quality Considerations

Eleuthero extract is a light brown powder with a faint, woody, slightly sweet odor and a mildly bitter, astringent taste. It is slightly soluble in water, so a solution turns hazy yellow-brown, with the glycosides largely dissolved and the less polar lignans and polyphenols in suspension. Eleutheroside E and eleutheroside B are glycosides and dissolve more readily than the lignans of the root.

The glycosides are stable at neutral to mildly acidic pH and moderate temperature, but hydrolyze under strong acid and in prolonged heat, and the polyphenols darken in the presence of iron. Stainless contact surfaces, low-iron fillers and light-protective packaging keep the shade steady. The sugar content makes the powder hygroscopic, so it cakes in humid air.

Scale-up of the root extract begins with a screen to break soft lumps, then a premix with part of the carrier and a weight check on the first fills. Drums are stored sealed and cool, with a desiccant liner in humid regions, and a closed charging system limits the tan dust that otherwise settles across the packing room.

Blends with other ingredients call for a brief pilot trial. Acidic ingredients can hydrolyze the glycosides in a liquid format held for months, and alkaline minerals speed oxidation of the polyphenols, so an accelerated stability study shows early whether a combination is sound.

Taste and mouthfeel are the last constraints in liquid formats. Eleuthero extract has a woody, slightly bitter and astringent profile that is far milder than most root extracts, and it blends well with citrus, apple and honey notes. At higher inclusion the astringency of the root phenolics builds, and a pinch of salt or a touch of fat softens it. Protein-containing drinks may show slight haze because the polyphenols bind protein, so a pilot trial at the target pH is a sensible step before scale-up.

Packaging & Commercial Supply

Essencefield supports product evaluation, formulation trials, commercial orders, and ongoing ingredient supply. Packaging, storage, and shipping arrangements are determined by product characteristics, order quantity, stability requirements, and destination-market needs.

Supply Item	General Information
Sample	Available upon request for formulation, testing, and supplier evaluation
Order Quantities	100 g · 1 kg · 5 kg · 25 kg · 100 kg · 500 kg · Bulk
Sample Lead Time	Typically 5–7 days after sample confirmation
Production Lead Time	Typically 15–30 days after order and specification confirmation
Packaging	Suitable protective inner packaging with bags, cartons, drums, or other appropriate outer packaging
Storage	Store in tightly sealed, suitable protective packaging in a cool, dry environment. Protect from moisture, heat, and direct sunlight. Specific storage conditions follow the approved product specification.
Documentation	COA · Product Specification · TDS · SDS · Applicable declarations (as applicable)

Final order quantities, lead times, packaging, documentation, and shipping arrangements are confirmed according to the selected product and commercial requirements.