Epimedium Extract Powder

Name: Epimedium Extract Powder 10% Icariin HPLC | Essencefield
SKU: BOT-BEX-0087

Epimedium Extract Powder is a botanical ingredient produced from medicinal Epimedium leaf material associated with Epimedii Folium. The genus belongs to the Berberidaceae family and is characterized by prenylated flavonol glycosides. The commercial ingredient is supplied as a concentrated powder for dietary supplement, nutraceutical, and botanical formulation projects.

Available standardized grades include 10% and 20% icariin measured by HPLC. The 10% grade serves as the principal commercial specification for general botanical formulations, while the higher-assay grade allows formulators to achieve the same target marker input with less extract mass. Both grades remain botanical extracts rather than purified single-compound ingredients.

SKU: BOT-BEX-0087 Categories: Botanical Extracts, Leaf & Herb Extracts Tags: Epimedium, Epimedium spp., Icariin, Prenylated Flavonoid Glycosides, Prenylflavonoids

Ingredient Profile & Common Uses

Epimedii Folium refers to the dried leaf of recognized medicinal Epimedium species including Epimedium brevicornu Maxim., Epimedium koreanum Nakai, Epimedium pubescens Maxim., and Epimedium sagittatum (Siebold & Zucc.) Maxim. Extract powder differs from simple milled leaf material because extraction concentrates characteristic flavonoids and produces a defined commercial ingredient for formulation and quality evaluation.

Commercial grades are differentiated by marker concentration rather than by botanical identity alone. A 10% grade retains a broader proportion of the plant extract matrix, while the 20% grade provides greater marker density and can reduce the amount of extract required in a finished formula. Ratio extracts and highly purified icariin represent different specification categories and should not be treated as direct equivalents.

The ingredient is used mainly in concentrated botanical supplements, multi-ingredient nutraceutical systems, and dry powder formulations. Conventional grades are not inherently clear water-soluble ingredients, so formulators should consider blend uniformity, wetting, haze, sedimentation, and sensory impact when moving from dry dosage formats into reconstituted or liquid systems.

Application Areas

Capsules

Epimedium extract can be incorporated into hard-shell capsule formulas where a defined marker level supports controlled ingredient loading and repeatable botanical formulation.

Tablets

The available assay grades are suitable for compressed supplements where formulators need to balance marker input, total tablet weight, excipient loading, powder flow, and blend uniformity.

Botanical Combination Formulas

The extract can be combined with other standardized botanicals in multi-component nutraceutical systems where quantified active-marker inputs simplify formula design and raw-material comparison.

Powder Blends & Sachets

Dry powder systems can incorporate the extract through appropriate premixing. Reconstituted products should be evaluated for wetting, suspension behavior, flavor interaction, haze, and sediment formation.

Typical Specifications

Specification	Information
Product Name	Epimedium Extract Powder
Botanical Genus	Epimedium L.
Botanical Family	Berberidaceae
Pharmaceutical Botanical Name	Epimedii Folium
Plant Material	Dried Leaf
Ingredient Type	Standardized Botanical Extract
Product Form	Powder
Main Marker	Icariin
Primary Grade	10% Icariin
Secondary Grade	20% Icariin
Analytical Method	HPLC
Assay Definition	Single-marker icariin content
Characteristic Chemical Class	Prenylated Flavonol Glycosides
Characteristic Constituents	Icariin · Epimedin A · Epimedin B · Epimedin C · Icaritin · Baohuoside I

Marker Compounds & Standardization

Icariin is a characteristic prenylated flavonol glycoside used as a principal analytical marker for Epimedium extracts. The botanical matrix also contains related compounds such as epimedin A, epimedin B, epimedin C, icaritin, and baohuoside I. Their relative distribution can differ among medicinal Epimedium species, making botanical identity and chromatographic profile relevant to ingredient evaluation.

HPLC provides compound-specific measurement of icariin within this more complex phytochemical matrix. This differs from UV-based methods that may report total icariins or broader flavonoid glycosides calculated against an icariin reference standard. Percentage values should therefore be interpreted together with the stated assay name and analytical method.

Highly purified material, such as icariin approaching 98%, contains substantially less of the original botanical matrix. It is better treated as a separate phytochemical ingredient rather than as a simple extension of the 10% or 20% botanical extract grades.

Technical & Quality Considerations

Quality evaluation should begin with botanical authentication and chromatographic identity rather than relying on assay percentage alone. Species-related differences can influence the relative profile of icariin and related flavonoids, so procurement and QA teams benefit from reviewing both raw-material identity and the HPLC fingerprint used to characterize the extract.

The ingredient behaves differently from a freely soluble small molecule. Icariin has poor aqueous solubility, and conventional extract powders may form haze, suspended solids, or sediment in water-based systems. A specifically engineered water-dispersible or water-soluble format should therefore be considered a separate formulation grade rather than an assumed property of the standard powder.

For capsules, tablets, and dry blends, scale-up should focus on uniform distribution and practical powder handling. When inclusion levels are relatively low, premixing with part of the formulation base can improve distribution before final blending. R&D teams should also evaluate flow, compression behavior, sensory contribution, and marker recovery in the finished product.

Packaging & Commercial Supply

Essencefield supports samples, development quantities, commercial orders, and repeat ingredient supply for product evaluation, formulation, and ongoing sourcing. Packaging, storage, and shipping conditions are selected according to ingredient characteristics, order quantity, stability requirements, and destination-market needs.

Supply Item	General Information
Sample	Available for formulation, testing, and supplier evaluation
Order Quantities	Sample · 100 g · 1 kg · 5 kg · 25 kg · 100 kg · 500 kg · Bulk
Sample Lead Time	5–7 days
Production Lead Time	15–30 days
Packaging	Sealed food-grade or suitable protective inner packaging with drum, carton, bag, or other appropriate outer packaging
Storage	According to the approved product specification and ingredient stability requirements
Documentation	COA · Product Specification · TDS · SDS · Applicable declarations

Available quantities, packaging format, net weight, storage conditions, analytical requirements, documentation, and shipping arrangements are confirmed according to the selected ingredient and commercial order.