Proanthocyanidin Standardization & Grades
Proanthocyanidins are condensed tannins, chains of flavan-3-ol units such as catechin and epicatechin joined by carbon bonds. The oligomeric fraction, abbreviated OPC, covers the short chains from dimers to pentamers, and the grade reports the total proanthocyanidin content of the extract. Grape seed is the plant part in which these tannins are concentrated, and the seed is a by-product of juice and wine pressing, dried before extraction. The botanical entity is Vitis vinifera L., and the part used is the seed.
The grade is a single level at 95%, so the choice is between grape seed and other grape materials, not between tiers. Skin and wine extracts carry different pigments and tannins and are supplied separately, as the Grape Skin Extract 10–25% Anthocyanins and the Red Wine Extract 30–50% Polyphenols. The seed is also supplied as a 10:1 ratio extract, the Grape Seed Extract Powder, which carries no marker figure. The 95% figure is a very high total, and it makes grape seed extract a concentrate of tannin, not a whole-seed extract. Seed oil is a different product that contains none of these polar tannins. Grape seed extract also differs from the pressed seed in its sensory profile: the seed is hard, woody and oily, whereas the extract is a fine, astringent powder with the oil removed. The monomers catechin and epicatechin sit at the base of every chain, and the chain length decides how strongly the tannin binds protein.












