Macamide Standardization & Grades
Macamides are N-benzylamides of long-chain fatty acids, lipophilic compounds that are specific to maca among common food crops. They are the standardization target because they set maca apart from other crucifer roots and because HPLC can resolve and quantify the individual members. The botanical entity is Lepidium meyenii Walp., and the part used is the swollen hypocotyl, the root that is dried and milled for the trade. Maca also holds glucosinolates, sterols and starch, but none of these defines the amide grade, and an extract can differ in all of them while sharing the same macamide figure.
| Grade | Assay & Method | Where It Fits |
|---|---|---|
| 0.6% Macamides | HPLC | Capsules and blended powders |
| 1% Macamides | HPLC | Compact capsules and tablets |
The two grades differ by less than a factor of two, so the choice is about fill size and cost per gram of marker. The 1% grade packs the macamide load into a smaller capsule. The 0.6% grade suits blends where the maca extract is one of several ingredients. Maca root is also supplied as a 10:1 ratio extract, the Maca Extract Powder, as a milled root, the Maca Root Powder, and as the Maca Peptide Powder, a peptide product that is a different material from a root extract. The fat-soluble nature of macamides is the reason ethanol extraction carries them, while a water-based route would leave most of them behind.












