Polygonum Cuspidatum Extract Powder

Polygonum Cuspidatum Extract Powder is a standardized botanical ingredient prepared from the root and rhizome of Japanese knotweed, commercially identified as Polygonum cuspidatum Sieb. et Zucc. and currently accepted botanically as Reynoutria japonica Houtt. The extract contains characteristic stilbenes and anthraquinones and is supplied as a concentrated powder for formulation use.

The primary commercial grade contains 50% trans-resveratrol by HPLC. Unlike highly purified resveratrol, this grade retains a broader root-derived phytochemical matrix containing polydatin, emodin, physcion, and related constituents. It is therefore positioned as a standardized Japanese knotweed extract rather than an isolated resveratrol ingredient.

SKU: BOT-BEX-0518 Categories: Botanical Extracts, Whole Plant & Specialty Extracts Tags: Antioxidant Support, Dietary Supplements, Polygonum, Polygonum cuspidatum, Polyphenols

Ingredient Profile & Common Uses

Japanese knotweed extract is produced from dried root and rhizome rather than aerial plant material. Extraction concentrates characteristic stilbenes, particularly resveratrol and its glycoside polydatin, together with anthraquinones including emodin and physcion. This composition differentiates the extract from simple botanical powder and from purified trans-resveratrol as an individual phytochemical.

Commercial grades are differentiated mainly by marker definition and assay concentration. A 50% standardized grade retains substantial botanical solids alongside the principal marker, giving it a different chemical and physical profile from higher-purity material. Extract ratio, total polyphenols, total resveratrol, and trans-resveratrol assay represent different specification systems and should not be treated as interchangeable.

The extract is used in dietary supplements, botanical combinations, functional nutrition, and selected cosmetic formulations. Its botanical matrix contributes visible color and limited aqueous dispersibility, while the resveratrol component requires consideration of light exposure and formulation environment. These characteristics make blend uniformity, dispersion, and physical compatibility relevant during product development.

Application Areas

Dietary Supplement Capsules and Tablets

Used in standardized botanical formulations where Japanese knotweed is selected as a defined source of resveratrol. Premixing and blend uniformity are important when the extract is incorporated at relatively low inclusion levels.

Botanical Combination Formulas

Suitable for multi-ingredient products containing polyphenol-rich botanicals. Formulators should distinguish the trans-resveratrol contribution from other standardized ingredients when calculating finished-product composition.

Powdered and Functional Nutrition

Applicable to dry blends, sachets, and selected functional nutrition systems. Product development should consider powder color, wetting, dispersion, sedimentation, and compatibility with other formulation components.

Cosmetic Formulation Development

Japanese knotweed extract is also evaluated in botanical cosmetic systems. Color compatibility, dispersion, light exposure, and formulation pH are relevant during ingredient screening and scale-up.

Typical Specifications

Parameter	Specification
Product Name	Polygonum Cuspidatum Extract Powder
Commercial Botanical Name	Polygonum cuspidatum Sieb. et Zucc.
Accepted Botanical Name	Reynoutria japonica Houtt.
Botanical Family	Polygonaceae
Common Name	Japanese Knotweed · Hu Zhang
Plant Part	Root and Rhizome
Ingredient Type	Standardized Botanical Extract Powder
Primary Commercial Grade	50% Trans-Resveratrol
Principal Marker	Trans-Resveratrol
Marker Assay	≥50.0%
Analytical Method	HPLC
Marker Chemical Class	Stilbene Polyphenol
Characteristic Stilbenes	Resveratrol · Polydatin / Piceid
Characteristic Anthraquinones	Emodin · Physcion
Product Form	Powder

Trans-Resveratrol Reference Identity

Property	Reference Information
Compound	Trans-Resveratrol
CAS Number	501-36-0
Molecular Formula	C14H12O3
Molecular Weight	228.24 g/mol
Chemical Family	Stilbene Polyphenol
Analytical Relevance	Principal standardization marker

The CAS number and molecular properties above apply to trans-resveratrol as an individual compound, not to the multi-component botanical extract.

Marker Compounds & Standardization

Trans-resveratrol is the principal marker used for standardized Polygonum cuspidatum extract, with HPLC providing specific quantitative measurement of the declared analyte. The assay definition is commercially important because trans-resveratrol, total resveratrol, total stilbenes, and total polyphenols represent different analytical measurements.

Polydatin, also known as piceid, is the glycosylated form of resveratrol and forms part of the characteristic stilbene profile of Japanese knotweed root and rhizome. Emodin and physcion represent the associated anthraquinone fraction. Their presence contributes to the broader chromatographic fingerprint that distinguishes a botanical extract from purified resveratrol.

For procurement and quality evaluation, the marker percentage should therefore be considered together with botanical identity and chromatographic profile. Emodin is particularly relevant during supplier qualification because its concentration can reflect differences in raw material selection, extraction, and purification strategy.

Technical & Quality Considerations

Incoming-material evaluation should focus on correct botanical identity, declared assay, analytical method, and chromatographic consistency. For a standardized 50% grade, HPLC results should clearly identify the measured trans-resveratrol content while also providing sufficient profile information to evaluate related stilbenes and anthraquinones. This helps distinguish genuine standardized extract from materials defined only by a broad or nonspecific polyphenol value.

The 50% botanical grade retains plant-derived solids that influence powder color, wetting, and dispersion. Trans-resveratrol itself has low aqueous solubility, while the behavior of the complete extract also reflects particle characteristics and the surrounding botanical matrix. Exposure to strong light should be minimized during formulation and handling because the trans isomer can undergo photoisomerization.

For dry manufacturing, R&D teams should evaluate premixing, blend uniformity, powder flow, capsule filling, and tablet compatibility. Liquid systems require additional assessment of wetting, haze, sedimentation, pH, and delivery strategy. Formulations requiring a clear aqueous appearance may need a suitable dispersion, encapsulation, or solubilization approach rather than direct addition of the standard extract powder.

Packaging & Commercial Supply

Essencefield supports product evaluation, formulation trials, commercial orders, and ongoing ingredient supply. Packaging, storage, and shipping arrangements are determined by product characteristics, order quantity, stability requirements, and destination-market needs.

Supply Item	General Information
Sample	Available upon request for formulation, testing, and supplier evaluation
Order Quantities	100 g · 1 kg · 5 kg · 25 kg · 100 kg · 500 kg · Bulk
Sample Lead Time	Typically 5–7 days after sample confirmation
Production Lead Time	Typically 15–30 days after order and specification confirmation
Packaging	Suitable protective inner packaging with bags, cartons, drums, or other appropriate outer packaging
Storage	Store in tightly sealed, suitable protective packaging in a cool, dry environment. Protect from moisture, heat, and direct sunlight. Specific storage conditions follow the approved product specification.
Documentation	COA · Product Specification · TDS · SDS · Applicable declarations (as applicable)

Final order quantities, lead times, packaging, documentation, and shipping arrangements are confirmed according to the selected product and commercial requirements.