Stephania tetrandra root extract powder 10:1 and 20:1

Stephania Tetrandra Extract Powder

Stephania Tetrandra Extract Powder is produced from the root of Stephania tetrandra S.Moore, traditionally known as Fang Ji or Stephaniae Tetrandrae Radix. This Menispermaceae botanical contains a characteristic isoquinoline alkaloid profile, with tetrandrine and fangchinoline serving as important compounds for ingredient identification and analytical evaluation.

Commercial ratio extracts are available in 10:1 and 20:1 grades, with 10:1 representing the primary commercial specification. These grades are multi-component botanical extracts rather than purified tetrandrine. High-purity tetrandrine is treated as a separate phytochemical ingredient because its analytical identity, physicochemical properties, and formulation behavior differ substantially from those of the whole root extract.

SKU: BOT-BEX-0581 Categories: Botanical Extracts, Root & Rhizome Extracts Tags: Antioxidant Support, Dietary Supplements, Polyphenols, Stephania, Stephania tetrandra

Ingredient Profile & Common Uses

The extract is derived from Stephania tetrandra root rather than whole-plant material or simple botanical powder. Current botanical taxonomy accepts the species as Botryodiscia tetrandra (S.Moore) L.Lian & Wei Wang, while Stephania tetrandra remains the established commercial and pharmaceutical name. Extraction concentrates soluble botanical constituents into a dry powder while retaining a broader root-derived chemical profile.

Commercial sourcing is centered on 10:1 and 20:1 ratio extracts, with 10:1 serving as the principal grade. The two specifications provide different concentration levels while remaining broader botanical extracts. They are commercially distinct from highly purified tetrandrine, which is better treated as an individual phytochemical rather than as another ratio grade of the same ingredient.

The powder is used in botanical ingredient development, natural-product research, analytical projects, and selected cosmetic formulation work. Its alkaloid-rich composition makes actual formulation testing important, particularly for wetting, dispersion, sedimentation, color contribution, and sensory impact. These characteristics should be assessed using the selected extract format rather than inferred from isolated tetrandrine.

Application Areas

Botanical Ingredient Formulations

Used in multi-botanical formulations where a defined Stephania root extract is required. Ratio grades provide concentrated botanical material while preserving a broader constituent profile.

Natural-Product Research

Suitable for research involving Stephania root chemistry, alkaloid profiling, botanical comparison, and evaluation of characteristic bisbenzylisoquinoline constituents.

Analytical Method Development

Applicable to botanical authentication, chromatographic fingerprinting, comparative ingredient analysis, and HPLC or LC-MS method development involving Stephania alkaloids.

Cosmetic Ingredient Evaluation

May be evaluated in botanical cosmetic development for compatibility, dispersion, color contribution, stability, and behavior within finished topical formulation systems.

Typical Specifications

Specification Item	Information
Product Name	Stephania Tetrandra Extract Powder
Botanical Name	Stephania tetrandra S.Moore
Accepted Taxonomic Name	Botryodiscia tetrandra (S.Moore) L.Lian & Wei Wang
Botanical Family	Menispermaceae
Common Name	Fang Ji
Pharmaceutical Name	Stephaniae Tetrandrae Radix
Plant Part	Root
Ingredient Type	Botanical Ratio Extract
Product Form	Powder
Available Ratio Grades	10:1 · 20:1
Primary Commercial Grade	10:1 Root Extract
Characteristic Alkaloids	Tetrandrine · Fangchinoline
Chemical Class	Bisbenzylisoquinoline alkaloids

Key Alkaloids & Extract Profile

Stephania tetrandra root contains a complex isoquinoline alkaloid profile. Tetrandrine and fangchinoline are among its best-characterized bisbenzylisoquinoline constituents and provide useful chemical markers when assessing botanical identity and chromatographic consistency.

Ratio extracts retain a broader mixture of root-derived constituents. This distinguishes them from highly purified tetrandrine, where a single compound has been extensively enriched and becomes the defining commercial specification.

Compound-level identifiers such as tetrandrine CAS number, molecular formula, molecular weight, and high-purity assay values therefore belong to a dedicated Tetrandrine product page. Assigning those properties to the complete botanical extract would incorrectly represent a multi-component ingredient as a single chemical substance.

Technical & Quality Considerations

Botanical authentication is especially important for Fang Ji materials because Stephania root has historically been confused with unrelated Aristolochia species. Quality evaluation should therefore emphasize authenticated source material and a characteristic alkaloid fingerprint. Tetrandrine and fangchinoline can support chromatographic identity assessment, while appropriate analytical screening can help distinguish the intended botanical from aristolochic-acid-containing substitution.

Physical behavior depends on the complete extract matrix rather than on one isolated alkaloid. Ratio extracts may differ in wetting, dispersibility, sedimentation, color, taste, and powder handling. These properties become particularly relevant in liquid, semi-liquid, or low-inclusion formulations where poor distribution can affect finished-product uniformity.

For scale-up, dry systems should be evaluated for blend uniformity and powder distribution. Premixing may improve consistency when inclusion levels are low. Liquid systems require additional attention to wetting sequence, agitation, suspension stability, precipitation, and filtration losses. Formulation development should therefore be based on the actual commercial extract rather than physicochemical data taken from purified tetrandrine.

Packaging & Commercial Supply

Essencefield supports product evaluation, formulation trials, commercial orders, and ongoing ingredient supply. Packaging, storage, and shipping arrangements are determined by product characteristics, order quantity, stability requirements, and destination-market needs.

Supply Item	General Information
Sample	Available upon request for formulation, testing, and supplier evaluation
Order Quantities	100 g · 1 kg · 5 kg · 25 kg · 100 kg · 500 kg · Bulk
Sample Lead Time	Typically 5–7 days after sample confirmation
Production Lead Time	Typically 15–30 days after order and specification confirmation
Packaging	Suitable protective inner packaging with bags, cartons, drums, or other appropriate outer packaging
Storage	Store in tightly sealed, suitable protective packaging in a cool, dry environment. Protect from moisture, heat, and direct sunlight. Specific storage conditions follow the approved product specification.
Documentation	COA · Product Specification · TDS · SDS · Applicable declarations (as applicable)

Final order quantities, lead times, packaging, documentation, and shipping arrangements are confirmed according to the selected product and commercial requirements.