Taxifolin 98%

Taxifolin, also known as dihydroquercetin or 2,3-dihydroquercetin, is a naturally occurring flavanonol structurally related to quercetin. Commercial Taxifolin 98% is supplied as a purified phytochemical powder with compound-level identity, rather than as a conventional botanical ratio extract or mixed-flavonoid preparation.

Essencefield supplies Taxifolin 98% for dietary supplement, functional food, beverage, and formulation projects requiring a defined dihydroquercetin concentration. The grade is positioned for procurement and development programs where consistent compound identity, controlled purity, and predictable formulation behavior are more important than broad botanical-extract composition.

SKU: BOT-PHY-0308 Categories: Phytochemicals, Flavonoids Tags: Antioxidant Support, Dietary Supplements, Flavonoids, Polyphenols, Taxifolin

Ingredient Profile & Common Uses

Taxifolin belongs to the flavanonol, or dihydroflavonol, subclass of flavonoids and has the molecular formula C15H12O7. It occurs naturally in several botanical materials, including conifer species, but commercial 98% material is handled primarily as an isolated phytochemical. Its chemical identity is therefore more precisely defined than that of a taxifolin-rich plant extract containing multiple phenolic constituents.

The primary commercial grade is Taxifolin 98%. This specification refers to the concentration of taxifolin itself; it is neither a 98:1 extract ratio nor a total-flavonoid value. Chromatographic methods such as HPLC are commonly used to evaluate the target compound and related-component profile, making analytical identity an important consideration when comparing commercial materials.

The ingredient is used in concentrated supplement, nutrition, functional food, and selected personal-care formulations. Its relatively low aqueous solubility influences formulation strategy, particularly in systems requiring complete dissolution. Dry applications are generally easier to manage through controlled premixing, while liquid development requires closer evaluation of dispersion and physical stability.

Application Areas

Dietary Supplements

Used in capsules, tablets, sachets, and powdered supplements where formulators require a defined dihydroquercetin ingredient rather than a broad-spectrum botanical flavonoid extract.

Functional Powder Blends

Suitable for concentrated nutrition and functional powder systems. Premixing with compatible powdered ingredients can improve distribution when taxifolin is used at relatively low inclusion levels.

Functional Food Development

Taxifolin can be evaluated for selected functional food applications requiring a defined flavanonol ingredient and controlled compound concentration.

Beverage Formulation

Beverage development requires evaluation of dispersion, visible haze, precipitation, and sedimentation because the compound does not readily dissolve in water at room temperature.

Personal Care Formulations

Taxifolin is also evaluated in selected cosmetic and personal-care systems where solvent selection, dispersion, crystal behavior, and compatibility with the finished matrix are relevant.

Typical Specifications

Parameter	Specification / Reference
Product Name	Taxifolin 98%
Compound Name	Taxifolin
Common Synonym	Dihydroquercetin
Additional Name	2,3-Dihydroquercetin
Ingredient Type	Purified Phytochemical
Product Form	Powder
Primary Specification	Taxifolin ≥98%
CAS Number	480-18-2
EC Number	207-543-4
PubChem CID	439533
Molecular Formula	C15H12O7
Molecular Weight	304.25 g/mol
Chemical Class	Flavanonol / Dihydroflavonol
Structural Relationship	2,3-Dihydro derivative of quercetin
Water Behavior	Low aqueous solubility
Published Equilibrium Solubility	Approximately 1.2 mg/mL under studied aqueous conditions

Compound Identity & Purity

Taxifolin is a pentahydroxylated flavanonol containing two stereogenic centers. The saturated C2–C3 bond differentiates its structure from the corresponding flavonol framework and is responsible for its classification as a dihydroflavonol. The widely referenced natural (+)-taxifolin form has the (2R,3R) configuration.

Chemical purity and stereochemical identity describe different analytical attributes. A 98% assay establishes the concentration of the target compound but does not, by itself, define the proportion of individual stereoisomeric forms. Where stereochemical composition is important to a formulation or research program, it should therefore be evaluated separately from routine quantitative assay.

For procurement purposes, this distinction also separates purified taxifolin from botanical materials standardized only by total flavonoids or broad extract composition. HPLC is commonly used to evaluate taxifolin assay and chromatographic profile, providing a more specific analytical basis than a generic total-flavonoid test.

Technical & Quality Considerations

Analytical evaluation should prioritize correct compound identity, quantitative assay, and chromatographic profile. These controls help distinguish the intended ingredient from related flavonoids and reveal whether significant secondary components are present. When a project specifies a particular stereochemical form, purity testing and stereochemical characterization should be treated as separate analytical questions.

Taxifolin has low aqueous solubility. Published research on taxifolin polymorphs reported equilibrium solubility of approximately 1.2 mg/mL under the studied aqueous conditions, with values around 1.149–1.281 mg/mL. Hydrated and anhydrous crystalline forms have also been identified, showing that crystal form can influence dissolution behavior even when chemical assay remains similar.

For dry formulations, blend uniformity is usually the main scale-up consideration. Premixing the concentrated ingredient with a larger powder fraction can improve distribution before final blending, encapsulation, or compression. In aqueous systems, R&D should evaluate wetting, dissolution, haze, precipitation, sedimentation, and processing conditions. These formulation variables are more informative than purity alone when predicting finished-product behavior.

Packaging & Commercial Supply

Essencefield supports product evaluation, formulation trials, commercial orders, and ongoing ingredient supply. Packaging, storage, and shipping arrangements are determined by product characteristics, order quantity, stability requirements, and destination-market needs.

Supply Item	General Information
Sample	Available upon request for formulation, testing, and supplier evaluation
Order Quantities	100 g · 1 kg · 5 kg · 25 kg · 100 kg · 500 kg · Bulk
Sample Lead Time	Typically 5–7 days after sample confirmation
Production Lead Time	Typically 15–30 days after order and specification confirmation
Packaging	Suitable protective inner packaging with bags, cartons, drums, or other appropriate outer packaging
Storage	Store in tightly sealed, suitable protective packaging in a cool, dry environment. Protect from moisture, heat, and direct sunlight. Specific storage conditions follow the approved product specification.
Documentation	COA · Product Specification · TDS · SDS · Applicable declarations (as applicable)

Final order quantities, lead times, packaging, documentation, and shipping arrangements are confirmed according to the selected product and commercial requirements.