Honokiol 98%

Honokiol is a purified botanical phytochemical associated with Magnolia officinalis Rehder & E.H.Wilson bark. Chemically classified as a biphenyl-type neolignan, it is a distinct compound rather than a conventional magnolia bark powder or broad-spectrum botanical extract. The commercial ingredient is supplied as a concentrated powder for formulation development, analytical evaluation, and professional ingredient sourcing.

Essencefield supplies an individual-compound grade containing not less than 98.0% honokiol by HPLC. This specification provides a defined phytochemical ingredient for projects requiring controlled compound identity and concentration rather than a mixed Magnolia extract standardized to multiple constituents.

Ingredient Profile & Common Uses

Honokiol occurs naturally in Magnolia officinalis and is commercially associated with magnolia bark as the botanical raw-material source. Its biphenyl structure contains phenolic hydroxyl and allyl groups that distinguish it chemically from general Magnolia extract matrices. Honokiol 98% therefore represents a purified phytochemical ingredient rather than whole bark powder, a ratio extract, or a broad standardized extract.

The 98% specification is intended for buyers who require honokiol itself to be the quantitatively defined ingredient. HPLC provides the analytical basis for measuring the individual compound and evaluating purity within a concentrated material. This grade architecture supports more precise formulation, analytical comparison, and supplier qualification than products defined only by total Magnolia phenols or a general extract ratio.

The concentrated compound is used in specialty botanical supplements, dry premixes, lipid-compatible delivery systems, and selected cosmetic formulations. Its lipophilic character and poor aqueous solubility influence ingredient handling and delivery-system selection. Accurate weighing, controlled preblending, and suitable dispersion strategies become particularly important when a small amount of concentrated material must be distributed uniformly through a finished formulation.

Application Areas

Capsules & Tablets

Suitable for concentrated solid-dose formulations where accurate weighing, geometric dilution, blend uniformity, powder flow, compression behavior, and assay recovery can be controlled during scale-up.

Dry Blends & Premixes

Honokiol can be incorporated into concentrated botanical premixes where controlled preblending helps distribute a relatively small quantity of active material throughout a larger powder system.

Softgel & Lipid-Based Systems

Its lipophilic profile makes oil carriers, lipid suspensions, phospholipid systems, and related non-aqueous delivery approaches practical starting points for formulation development.

Emulsified & Cosmetic Systems

Honokiol can be evaluated in emulsions, anhydrous bases, and deliberately solubilized systems where crystallization, ingredient distribution, compatibility, and physical stability can be monitored.

Typical Specifications

ItemSpecification / Reference Property
Product NameHonokiol 98%
CompoundHonokiol
Botanical SourceMagnolia officinalis Rehder & E.H.Wilson
Plant PartBark
Ingredient TypePurified Botanical Phytochemical
Product FormPowder
Primary Specification≥98.0% Honokiol
Analytical MethodHPLC
CAS Number35354-74-6
EC Number609-119-8
PubChem CID72303
UNII11513CCO0N
Molecular FormulaC18H18O2
Molecular Weight266.33 g/mol
Chemical ClassBiphenyl-Type Neolignan
Water BehaviorPoorly soluble in water
Related Magnolia CompoundMagnolol

Typical Specifications

ItemSpecification / Reference Property
Product NameHonokiol 98%
CompoundHonokiol
Botanical SourceMagnolia officinalis Rehder & E.H.Wilson
Plant PartBark
Ingredient TypePurified Botanical Phytochemical
Product FormPowder
Primary Specification≥98.0% Honokiol
Analytical MethodHPLC
CAS Number35354-74-6
EC Number609-119-8
PubChem CID72303
UNII11513CCO0N
Molecular FormulaC18H18O2
Molecular Weight266.33 g/mol
Chemical ClassBiphenyl-Type Neolignan
Water BehaviorPoorly soluble in water
Related Magnolia CompoundMagnolol

Technical & Quality Considerations

Analytical evaluation should prioritize compound identity, individual honokiol assay, and adequate chromatographic resolution of closely related components. During supplier qualification, the chromatographic profile can provide useful information beyond the headline assay when comparing development samples with subsequent commercial lots. Consistent analyte definition is also important for internal specifications, incoming inspection, and finished-product assay recovery.

The compound has poor compatibility with simple water-based systems. Direct addition to water can result in incomplete wetting, suspended particles, recrystallization, or sedimentation rather than a true solution. Lipid phases, suitable solvent systems, phospholipids, emulsification, encapsulation, or other delivery technologies can be evaluated when liquid incorporation is required. Prototype stability work should include visual monitoring for precipitation or recrystallization after storage and temperature cycling.

At production scale, a concentrated assay may require only a relatively small ingredient weight within the total blend. Accurate weighing and geometric dilution can therefore become important controls. Dry products should be evaluated for blend uniformity, flow, capsule filling, compression, and analytical recovery. Lipid and emulsified systems should be evaluated for settling, crystallization, viscosity, ingredient distribution, and physical stability throughout the intended product life cycle.

Packaging & Commercial Supply

Essencefield supports product evaluation, formulation trials, commercial orders, and ongoing ingredient supply. Packaging, storage, and shipping arrangements are determined by product characteristics, order quantity, stability requirements, and destination-market needs.

Supply ItemGeneral Information
SampleAvailable upon request for formulation, testing, and supplier evaluation
Order Quantities100 g · 1 kg · 5 kg · 25 kg · 100 kg · 500 kg · Bulk
Sample Lead TimeTypically 5–7 days after sample confirmation
Production Lead TimeTypically 15–30 days after order and specification confirmation
PackagingSuitable protective inner packaging with bags, cartons, drums, or other appropriate outer packaging
StorageStore in tightly sealed, suitable protective packaging in a cool, dry environment. Protect from moisture, heat, and direct sunlight. Specific storage conditions follow the approved product specification.
DocumentationCOA · Product Specification · TDS · SDS · Applicable declarations (as applicable)

Final order quantities, lead times, packaging, documentation, and shipping arrangements are confirmed according to the selected product and commercial requirements.

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